Careers

X4 offers a place where patient-focus is our priority and encourage people who share this value to apply. We offer a team-based approach in a collegial environment. We place a high importance on individual career development to enable one to meet his or her professional goals.

X4 is seeking key team members who:

  • Problem solve and who execute with high precision.
  • Say what they mean, and let their words match their actions.
  • Enjoy a team environment and foster direct and open communications

X4 is an equal opportunity employer and offers a comprehensive and competitive benefits package. Full-time employees are eligible for all benefits on their date of hire.

  • Health plan
  • Dental plan
  • Life/ADD insurance
  • Short- and long-term disability insurance
  • 401(k) plan for retirement savings
  • Subsidized parking or MBTA pass
  • Competitive Paid Time Off / Holidays

Open Positions

Vice President, Clinical Operations

Company Description:

X4 Pharmaceuticals is developing novel therapeutics designed to improve immune cell trafficking including the ability for T-cells to track and destroy cancer cells. Our small molecule drug candidates inhibit C-X-C receptor type 4 (CXCR4), a receptor over-expressed in many cancers. Inhibition of CXCR4 is designed to block non-cancerous immunosuppressive and pro-angiogenic cells from populating the tumor, disrupting the cancer microenvironment and restoring normal immune surveillance functions. We are committed to advancing the field of cancer immunotherapy and immune disorders through innovation and investment in our proprietary clinical and preclinical pipeline.

Reporting to the Chief Medical Officer, the Vice President, Clinical Operations is an experienced leader with a focus on strategic planning and execution of clinical trials to gain regulatory approval of current and future X4 programs. The incumbent will have a proven track record of leading and planning to ensure that program goals are met timely, efficiently, and on budget. This position requires someone that is a self-starter and can act in different roles within this position to support the mission of X4. This position also includes direct staff management, training and development; serving as a leader of the company with impactful involvement on leadership decisions, meetings, etc. This position requires a well-rounded individual to lead in various areas of Clinical Operations that can provide insight, advisement, and clarity into various day-to-day Clinical Operations tasks.

A proven leader of people and process with an uncompromised commitment to the Patient.

Scope of Work and Responsibilities:

  • Lead Cinical Operations, Data Management, Biostatistics and Medical Writing internal functions or with external service providers
  • Assist in the strategic development and execution of various clinical trials, ensures timeliness and budgets are achieved
  • Creates and manages to clinical budgets
  • Lead the selection and evaluation and effectiveness of CROs, sets standards for evaluation of CROs and reviews regularly
  • Interacts with external vendors and clients such as investigator sites, CROs, CRAs, and other vendors
  • Responsible for ensuring efficient and effective study formulation and implementation
  • Coordinates data analysis and ensures accuracy and timeliness
  • Interacts with the FDA and other global regulatory agencies
  • Certifies continuous compliance in clinical trials
  • Reviews and edits study protocols, outlines, amendments, and Investigator brochures

Qualifications and Professional Skills:

  • Bachelor’s degree in related field
  • 10+ years of relevant Clinical Operations experience in Biotech/Biopharma
  • Experience with IND and NDA submissions
  • Familiar and comfortable with clinical operations concepts and operational practices and needs
  • History of successful management and interaction and on-going process improvement with CROs, vendors, and other external partners
  • Proven team member that can work independently and collaboratively
  • Detail oriented and able to guide Clinical Operations improvements in a rapidly changing climate growing companyExperience in FDA regulations, other international regulatory agencies
  • Prior experience successfully managing and developing direct report(s)
  • Proven track record of managing multiple projects and/or programs concurrently
  • Self-starter with a positive work ethic

The above statements are intended to describe the general nature and level of work being performed.  They are not intended to be construed as an exhaustive list of all responsibilities.

X4 Pharmaceuticals is an Equal Opportunity and Affirmative Action Employer committed to a culturally diverse workforce.  All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law.   Please send your resume and cover letter to careers@x4pharma.com

We invite you to apply for any of our current openings at careers@x4pharma.com for additional employment related information.