Careers

X4 offers a place where patient-focus is our priority and encourage people who share this value to apply. We offer a team-based approach in a collegial environment. We place a high importance on individual career development to enable one to meet his or her professional goals.

X4 is seeking key team members who:

  • Problem solve and who execute with high precision
  • Say what they mean, and let their words match their actions
  • Enjoy a team environment and foster direct and open communications

X4 is an equal opportunity employer and offers a comprehensive and competitive benefits package. Full-time employees are eligible for all benefits on their date of hire.

  • Health plan
  • Dental plan
  • Life/ADD insurance
  • Short- and long-term disability insurance
  • 401(k) plan for retirement savings
  • Subsidized parking or MBTA pass
  • Competitive Paid Time Off / Holidays

Open Positions

Director / Senior Director, Pharmacovigilance

Company Description:

Our grit drives our commitment to find solutions for patients. Every day, we strive to advance our pipeline of innovative medicines to treat rare diseases.

X4 was founded and is led by a team with deep product development and commercialization expertise, including several former members of the Genzyme leadership team and is located in Cambridge, MA.

Our first-in-class, oral, small molecule therapeutics are antagonists of chemokine receptor CXCR4, which have the potential to treat a broad range of rare diseases, including primary immunodeficiencies (PIs) and cancer. A number of PIs are attributed to the improper trafficking of immune cells related to the CXCR4 receptor and its ligand CXCL12.

 

Company Culture:
X4 is an innovative, global, publicly traded company that offers strong growth potential and a stimulating environment. As a tight-knit team of employees, we are dedicated high-achievers, and above all else, passionate about what we do. We take pride in our employee-focused atmosphere where each person’s contribution is vital to our success. People here are pro-active, enthusiastic about being given the opportunity to define, develop and shape the company.

Employees thrive in this autonomous and fast-paced environment where success is based on contribution and work ethic, not on title or rank. Our leaders have open doors and employees are encouraged to make decisions, speak their opinions and get things done. Employees are empowered to think creatively, share ideas and are able to translate strategies into action.

X4 has built a reputation for putting the patient first and foremost, as well as a values-driven work style where integrity and grit drive all behaviors, decisions and actions.

 

What’s in it for you?

In this highly visible role you will report directly to the Chief Medical Officer. You will be an engaged partner and have an opportunity to have your voice heard. In turn, your experience includes strategy to tactics, while remaining flexible, proactive, and resourceful. You will be able to analyze complex issues to develop relevant and realistic plans, programs and provide your recommendations. Your excellent interpersonal skills, experience developing strategic and long-term relationships with key stakeholders, and proven conflict management and negotiation skills will be utilized to their fullest.

You will create, direct and manage the company’s infrastructure to support the operational aspects of the pharmacovigilance system and adhere to all global safety requirements and internal processes and procedures. You will translate strategy into action with your excellent analytical skills and the keen ability to clearly communicate complex issues and orchestrate plans to mitigate risks.

Finally, you will build and maintain sustained and trusting relationships with key strategic internal and external stakeholders, provide leadership for interactions with health authorities, and support review and development of regulatory submissions and PV activities.

 

Key competencies for success:

Excellence: Do all things with rigor.

Accountability: Hold each other and ourselves accountable for our actions and to live our values.

Camaraderie: Work together as a team aligned to achieve our goals and be respectful of each other.

Integrity: Act with honesty and transparency.

Sense of Urgency: Demonstrate a higher sense of purpose: to alleviate human suffering and cure disease.

Grit: Move forward with firmness of mind and unyielding courage.

 

What we need from you:

  • Bachelor’s degree in life sciences, pharmacy, nursing or equivalent health experience; advanced Life Sciences Degree or MBA a plus.
  • Proven experience in a Drug Safety / Pharmacovigilance role in all phases of drug development in the biotech or pharmaceutical industry.
  • Demonstrated ability to create, evaluate and maintain effective business processes, implement procedures, systems and tools to maximize budget and resources within a Drug Safety department.
  • Thorough knowledge and experience in all aspects of global safety reporting for clinical trials through commercialization.
  • Strong knowledge and experience with currently available drug safety database systems, document management systems and QC tools. This also includes MedDRA and linked technologies.
  • Operational expertise with safety databases such as ARGUS is preferred.
  • Experience in supporting regulatory agency meetings and/or inspections is a plus
  • Excellent oral, electronic and written communication skills.
  • Strong interpersonal, collaboration and leadership skills and demonstrated ability to motivate and influence work behaviors of individuals who are not direct reports
  • A reputation that reflects embracing the core values and the mission of X4.

 

The above statements are intended to describe the general nature and level of work being performed. They are not intended to be construed as an exhaustive list of all responsibilities.

X4 Pharmaceuticals is an Equal Opportunity and Affirmative Action Employer committed to a culturally diverse workforce. All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law. Please send your resume and cover letter to careers@x4pharma.com

Manager / Senior Manager, Project Management

Company Description:

X4 is focused on restoring healthy immune system function by developing novel therapeutics for the treatment of rare diseases.

Our first-in-class, oral, small molecule therapeutics are antagonists of chemokine receptor CXCR4, which have the potential to treat a broad range of rare diseases, including primary immunodeficiencies (PIs) and cancer. A number of PIs are attributed to the improper trafficking of immune cells related to the CXCR4 receptor and its ligand CXCL12.

X4’s lead product candidate, X4P-001, has completed a Phase 2 trial in patients with a rare genetic PI called Warts, Hypogammaglobulinemia, Infections, and Myelokathexis, or WHIM syndrome. X4 plans to initiate a Phase 3 pivotal trial of X4P-001 in patients with WHIM syndrome. In addition to the initial focus on WHIM syndrome, X4 believes that the biological rationale and available data on X4P-001 support potential therapeutic benefits across a broad range of PIs, including Severe Congenital Neutropenia and certain lymphomas, such as Waldenstrom Macroglobulinemia.

X4 is also developing X4P-002, a CXCR4 antagonist that has unique properties that the company believes will enable penetration of the blood-brain barrier and provide appropriate therapeutic exposures to treat brain cancers, including glioblastoma multiforme (GBM).

Reporting to the Senior Director, Program Management, the Manager, Project Management will apply established business principles in a scientific setting, and work with the Senior Director, Program Management to manage one or more drug development programs. This person will support the development and execution of high quality, global, integrated cross-functional plans for one or more drug development programs. They will also be expected to apply project management best practices in the development, initiation, planning, execution, maintenance, and closing of projects. This person will contribute to management and continuous improvement of a recently implemented portfolio governance structure.

The Manager/Sr. Manager will also highlight risks, timeline delays and other issues to the organization by preparing presentation materials and participating in discussions with senior executive members. The candidate will be a team player with well-developed skills for gaining the cooperation of others and ensuring effective communication among team members. Previous biotech/bio pharma, drug discovery/development and project management experience at all levels of the organization is required.

To succeed at X4, the candidate will have a sustained reputation for putting the patient first and foremost, as well as a values-driven work style where integrity and grit drive all behaviors, decisions and actions.

 

Scope of Work and Responsibilities:

  • Creates and maintains high quality integrated project plans and ensures alignment between overall program strategy and cross functional plans.
  • Communicates timely project status through monthly dashboards and other reporting materials. Assuring collection reporting
  • Assists with program team and portfolio steering committee meetings as needed (may include writing and distributing meeting minutes and following up on action items with cross functional colleagues at all levels)
  • May independently manage sub-teams of the program team
  • Assists with risk mitigation planning
  • Facilitates financial planning process by integrating input from functions and project teams
  • Supports department initiatives as needed
  • Experience and application of project management best practices and processes

 

Communication:

  • Provides project information to Senior Director, Program Management for incorporation into strategic deliverables, program timelines, and portfolio discussions
  • Provides project information at functional sub-team meetings and to other cross functional stakeholders
  • Escalates project issues and risk mitigations to Senior Director of Program Management or functional sub-team leader in a timely manner
  • Assist head of program management with development of Governance Board deliverables as needed

 

Qualifications and Professional Skills:

  • BS/BA. Advanced degree in scientific discipline is preferred or strong demonstration of equivalent combination of relevant educational and professional training
  • Six (6) to Eight (8) years industry experience in the Biotechnology, Pharmaceutical, or other Healthcare related field
  • At least three (3) years of experience in a pharmaceutical Project Management role
  • Drug Development knowledge with basic to strong understanding of other functions which include: Research, Pre-Clinical, Clinical, Manufacturing & Operations, Commercial, and Regulatory Affairs
  • Strong interpersonal skills with experience leading cross-functional teams in matrix environment preferred.
  • Reputation for success working in fast-changing environments, showing comfort with ambiguity.
  • Proficient with Project Management best practices and tools, including MS Project
  • Quick learner, goal oriented and results driven with excellent problem-solving skills and proven experience escalating issues appropriately
  • Excellent verbal and written communication skills

 

The above statements are intended to describe the general nature and level of work being performed. They are not intended to be construed as an exhaustive list of all responsibilities.

X4 Pharmaceuticals is an Equal Opportunity and Affirmative Action Employer committed to a culturally diverse workforce. All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law. Please send your resume and cover letter to careers@x4pharma.com

Office Services Specialist - Culture Ambassador

Company Description:

Our grit drives our commitment to find solutions for patients. Every day, we strive to advance our pipeline of innovative medicines to treat rare diseases.

X4 was founded and is led by a team with deep product development and commercialization expertise, including several former members of the Genzyme leadership team and is located in Cambridge, MA.

Our first-in-class, oral, small molecule therapeutics are antagonists of chemokine receptor CXCR4, which have the potential to treat a broad range of rare diseases, including primary immunodeficiencies (PIs) and cancer. A number of PIs are attributed to the improper trafficking of immune cells related to the CXCR4 receptor and its ligand CXCL12.

 

Company Culture:

X4 is an innovative, global, publicly traded company that offers strong growth potential and a stimulating environment. As a tight-knit team of employees, we are dedicated high-achievers, and above all else, passionate about what we do. We take pride in our employee-focused atmosphere where each person’s contribution is vital to our success. People here are pro-active, enthusiastic about being given the opportunity to define, develop and shape the company.

Employees thrive in this autonomous and fast-paced environment where success is based on contribution and work ethic, not on title or rank. Our leaders have open doors and employees are encouraged to make decisions, speak their opinions and get things done. Employees are empowered to think creatively, share ideas and are able to translate strategies into action.

X4 has built a reputation for putting the patient first and foremost, as well as a values-driven work style where integrity and grit drive all behaviors, decisions and actions.

 

What’s in it for you?

In this newly created and highly visible role you will play an essential part in supporting the whole company, providing high touch office services, and being a leader of our company culture. The Office Services Specialist will report to the Office Manager/EA to the CEO and work closely with the Executive Administrative Team. You will be responsible for performing a wide array of office support services that require integrity, initiative and resourcefulness. This position requires a reputation for attention to detail, sound decision-making, and discretion given the access to sensitive, non-public confidential information.

 

Key competencies for success aligned with X4’s values:

Excellence: Do all things with rigor.

Accountability: Hold each other and ourselves accountable for our actions and to live our values.

Camaraderie: Work together as a team aligned to achieve our goals and be respectful of each other.

Integrity: Act with honesty and transparency.

Sense of Urgency: Demonstrate a higher sense of purpose: to alleviate human suffering and cure disease

Grit: Move forward with firmness of mind and unyielding courage.

 

What we need from you:

You are an energetic, passionate self-starter who thrives in fast-paced environments. You are bored easily, and always proactive to keep your plate full and wear many hats. You are a go-getter and the type of person who considers herself/himself a high achiever. You enjoy meeting and greeting visitors and being a face of the organization. You are skilled in responding to unpredictable situations with a smile, have a positive attitude and a great sense of humor.

You have been rewarded for your strong organizational skills and project management abilities. You have proven experience working effectively with all levels of an organization, both internally and with external visitors. Your experience includes successfully balancing multiple competing priorities simultaneously ensuring a smooth and efficient flow of the day-to-day operations. You are a reliable, patient, and ambitious person who takes their career very seriously looking to learn and grow.

 

Required qualifications:

  • Bachelor’s degree and 2- 5 years office services/receptionist experience in a fast-paced, high touch environment managing multiple responsibilities, timelines and priorities simultaneously
  • Growing/small company or start up strongly preferred, as well as experience in Biotech
  • Previous responsibilities to include: vendor management (supplies, facilities, food services), budget creation and accountabilities, front desk duties, office and kitchen supply inventory, catering processes, employee events and general office duties.
  • Experienced problem solver with the ability to collaborate in a team environment and also the ability to work independently with minimal supervision.
  • Highly competent in office technology and machines, Outlook, Microsoft Office 365 (word, excel, PowerPoint), Adobe Acrobat, and Social Media web platform.
  • Project management – proven ability to plan, execute and deliver on time and within budget
  • Reputation for attention to detail and exceptional organizational skills
  • Confidentiality – exercises discretion handling confidential material and information
  • Professionalism – easily approachable, positive can-do attitude, communicates effectively verbally, written and electronic. Possesses interpersonal skills to work with internal and external partners at varying levels.

 

The above statements are intended to describe the general nature and level of work being performed. They are not intended to be construed as an exhaustive list of all responsibilities.

X4 Pharmaceuticals is an Equal Opportunity and Affirmative Action Employer committed to a culturally diverse workforce. All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law. Please send your resume and cover letter to careers@x4pharma.com

Senior Executive Assistant to CFO

Company Description:

Our grit drives our commitment to find solutions for patients. Every day, we strive to advance our pipeline of innovative medicines to treat rare diseases.

X4 was founded and is led by a team with deep product development and commercialization expertise, including several former members of the Genzyme leadership team and is located in Cambridge, MA.

Our first-in-class, oral, small molecule therapeutics are antagonists of chemokine receptor CXCR4, which have the potential to treat a broad range of rare diseases, including primary immunodeficiencies (PIs) and cancer. A number of PIs are attributed to the improper trafficking of immune cells related to the CXCR4 receptor and its ligand CXCL12.

 

Company Culture:

X4 is an innovative, global, publicly traded company that offers strong growth potential and a stimulating environment. As a tight-knit team of employees, we are dedicated high-achievers, and above all else, passionate about what we do. We take pride in our employee-focused atmosphere where each person’s contribution is vital to our success. People here are pro-active, enthusiastic about being given the opportunity to define, develop and shape the company.

Employees thrive in this autonomous and fast-paced environment where success is based on contribution and work ethic, not on title or rank. Our leaders have open doors and employees are encouraged to make decisions, speak their opinions and get things done. Employees are empowered to think creatively, share ideas and are able to translate strategies into action.

X4 has built a reputation for putting the patient first and foremost, as well as a values-driven work style where integrity and grit drive all behaviors, decisions and actions. 

 

What’s in it for you?

In this highly visible role you will support our visionary CFO and will act as his trusted right hand. You are forward-thinking, business savvy and enjoy proactively suggesting projects, improvements and opportunities.

You will be recognized for your ability to think on your feet- creatively and collaboratively- amidst ambiguity.  You are organized and motivated, confident, yet balanced, and you have a sincere passion for optimizing time and productivity. You have an innate sense of urgency and on-the-fly problem solving skills paired with a can-do attitude

You are analytical, professional, tenacious, kind and persuasive all rolled into one.

 

Summary of role:

  • Meeting Coordination: Works with the CFO to organize and coordinate major meetings. Follows-up on deadlines for assigned activities including Board of Directors meetings and committee meetings, senior staff meetings, outside meetings, and committee work. Manage CFO calendar.
  • Documentation (Reports) Preparation: Prepares talking points for presentations, reports, and narratives. Conducts background research to support the CFO in preparing reports, and other materials. Compiles and analyzes data and prepares reports as requested.
  • Leadership Team Membership: Represents and supports the CFO internally and externally in meetings, committees, and phone calls when appropriate.
  • Coordination of Meetings, Travel and Events: Works with CFO to perform tasks required to arrange select Board Committee meetings, prepares Board committee minutes, maintains Board Committee files and performs other administrative for the Board Committees as needed.
  • Project Planning, Management, and Participation: Participates in or leads projects delegated by the CFO. Contributes to the strategic prioritization of tasks, initiatives, and projects identified by the CFO.
  • Administration: Manage and field all incoming phone calls, act as a liaison with other business units, serve as back-up for office operations as needed, proactively anticipate administrative needs of CFO.
  • Project Management and Participation: Leads, manages or participates on cross-functional project teams.
  • Human Resources: Additional support to the VP Human Resources and her Team with a variety of operational and confidential organizational activities.

 

Key competencies for success aligned with X4’s values:

Excellence: Do all things with rigor.

Accountability: Hold each other and ourselves accountable for our actions and to live our values.

Camaraderie: Work together as a team aligned to achieve our goals and be respectful of each other.

Integrity: Act with honesty and transparency.

Sense of Urgency: Demonstrate a higher sense of purpose: to alleviate human suffering and cure disease

Grit: Move forward with firmness of mind and unyielding courage.

 

What we need from you:

  • Minimum of 8 years’ experience as an Executive Assistant in a high growth, publicly traded company.
  • Proven experience supporting C-Level Executive(s) and/or Senior Executive(s)
  • Previous experience in Life Sciences/Technology/Finance/Investor Relations sectors a plus.
  • Thrives in a changing and fast-paced environment while remaining poised and focused.
  • Business-savvy with a proactive nature- always thinking ahead and “seeing around corners.”
  • Outstanding written, verbal and electronic communication skills are required as a critical voice of the company, both externally and on behalf of the CFO.
  • Reputation for successful engagement with all levels of the organization and external partners

 

The above statements are intended to describe the general nature and level of work being performed.  They are not intended to be construed as an exhaustive list of all responsibilities. 

X4 Pharmaceuticals is an Equal Opportunity and Affirmative Action Employer committed to a culturally diverse workforce.  All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law.   Please send your resume and cover letter to careers@x4pharma.com

 

Accounting Manager

Company Description:

Our grit drives our commitment to find solutions for patients. Every day, we strive to advance our pipeline of innovative medicines to treat rare diseases.

X4 was founded and is led by a team with deep product development and commercialization expertise, including several former members of the Genzyme leadership team and is located in Cambridge, MA.

Our first-in-class, oral, small molecule therapeutics are antagonists of chemokine receptor CXCR4, which have the potential to treat a broad range of rare diseases, including primary immunodeficiencies (PIs) and cancer. A number of PIs are attributed to the improper trafficking of immune cells related to the CXCR4 receptor and its ligand CXCL12.

 

Company Culture:

X4 is an innovative, global, publicly traded company that offers strong growth potential and a stimulating environment. As a tight-knit team of employees, we are dedicated high-achievers, and above all else, passionate about what we do. We take pride in our employee-focused atmosphere where each person’s contribution is vital to our success. People here are pro-active, enthusiastic about being given the opportunity to define, develop and shape the company.

Employees thrive in this autonomous and fast-paced environment where success is based on contribution and work ethic, not on title or rank. Our leaders have open doors and employees are encouraged to make decisions, speak their opinions and get things done. Employees are empowered to think creatively, share ideas and are able to translate strategies into action.

X4 has built a reputation for putting the patient first and foremost, as well as a values-driven work style where integrity and grit drive all behaviors, decisions and actions. 

 

What’s in it for you?

In this exciting role you will report to the Controller/Senior Director Finance and will be responsible for the day-to-day operations of the Accounting department including the management of the month-end close process, accounts payable and treasury function. This is a highly visible role and will also assist with other activities to support the company’s growth, such as budgeting and financial analysis, equity administration, management reporting, and other ad hoc projects as needed.

The position requires professionalism and discretion, the ability to multi-task while delivering high quality work, and the capability to work effectively in a rapidly changing environment.  The role will interact closely with all levels of management and staff, as well as outside service providers (auditors, vendors, consultants, attorneys, etc.).

To succeed at X4, the candidate will have a sustained reputation for a values-driven, collaborative, engagement style where integrity and the consideration of our Patients drives all decisions and actions.

 

Summary of role:

  • Build and manage the accounting function consisting of the monthly closing process, general ledger, and accounts payable
  • Manage all day-to-day accounts payable operations, including vendor management, invoice entry, and payments
  • Manage the Company’s corporate credit cards and related monthly reconciliation
  • Support the audit process and SEC reporting
  • Assist in the preparation of budgets, forecasts, and financial analysis
  • Support compliance across the company including tax filings, implementation of controls, and governance
  • Create and update policies and process documents as needed
  • Manage the ERP system and other ancillary systems and processes to insure accurate and efficient reporting
  • Special projects and other tasks as assigned

 

Key competencies for success aligned with X4’s values:

Excellence: Do all things with rigor.

Accountability: Hold each other and ourselves accountable for our actions and to live our values.

Camaraderie: Work together as a team aligned to achieve our goals and be respectful of each other.

Integrity: Act with honesty and transparency.

Sense of Urgency: Demonstrate a higher sense of purpose: to alleviate human suffering and cure disease

Grit: Move forward with firmness of mind and unyielding courage.

 

What we need from you:

  • Bachelor’s degree in Accounting or Finance required
  • Over 5 years of experience, public accounting and/or life science/biotech/technology strongly preferred
  • Previous experience in a high growth or start up environment a plus
  • Experience with complex US GAAP principles including stock-based compensation accounting, consolidations, debt, and foreign currency translation
  • Understanding of Sarbanes-Oxley (“SOX”) documentation and requirements
  • Strong expertise with ERP systems, experience with NetSuite a plus
  • Outstanding verbal, written and technology communication skills successfully working with all levels of the organization
  • High proficiency with Microsoft Office suite (PowerPoint, Excel, and Word)
  • Proven effectiveness in time management, attention to detail and organizational skills
  • Proven history keeping sensitive information confidential
  • Understanding of accounting policies, processes, procedures, and internal controls at a public company
  • Ability to adapt quickly and learn new tasks independently
  • Ability to manage competing priorities in order to meet deadlines
  • Demonstrates a sense of urgency, proactive thinking, and productivity in a fast-paced, entrepreneurial and team-oriented environment.

 

The above statements are intended to describe the general nature and level of work being performed.  They are not intended to be construed as an exhaustive list of all responsibilities.

X4 Pharmaceuticals is an Equal Opportunity and Affirmative Action Employer committed to a culturally diverse workforce.  All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law.   Please send your resume and cover letter to careers@x4pharma.com

We invite you to apply for any of our current openings at careers@x4pharma.com for additional employment related information.

 

X4 Pharmaceuticals does not review or control the content on the website to which this hyperlink connects and this hyperlink does not constitute an endorsement by X4 Pharmaceuticals of the content of any non-X4 Pharmaceuticals website.

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