Our grit and science drive solutions for patients. Every day, we strive to advance our pipeline of innovative therapeutic candidates to treat rare diseases. We are targeting the CRCX4 pathway, one of the most important chemokine pathways, in an effort to treat people with rare immune system disorders.

Primary Immunodeficiency (PI) Diseases

Aberrant functioning of CXCR4 is associated with certain PI diseases. X4 has now completed enrollment in its pivotal Phase 3 clinical trial for its lead candidate, mavorixafor, in patients with WHIM syndrome.

Pipeline

X4 is developing novel, oral medicines designed to treat a range of rare diseases, including primary immunodeficiency diseases and certain rare cancers, such as lymphomas.

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