- Neutropenia is a complex disease, marked by having a low number of neutrophils, a type of white blood cell. The lower the neutrophil count, the greater the risk of infection.
- Neutropenia can be described as chronic, congenital (from birth), or cyclical neutropenia. Not all specialists describe neutropenia the same way and not all describe it as a type of primary immunodeficiency.
- Congenital neutropenia is both a rare blood disorder and a rare type of primary immunodeficiency (PID).
- People living with neutropenia have few treatment options. More treatment options are needed.
- X4 Pharmaceuticals is conducting a Phase 1b clinical trial to help researchers answer questions about the study drug, mavorixafor, and what impact it may have after one dose.
- ClinicalTrials.gov –listing for the X4 study (NCT Identifier: 04154488)
- IDYourPID—sponsored by X4 Pharmaceuticals, this website includes information about genetic testing and primary immunodeficiencies, including neutropenia.
- National Neutropenia Network—promotes awareness, education, and research about neutropenia and provides a support system for patients and families.